DNA unpacking
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tools to address a bottleneck of non-viral gene delivery - NCBI2009年9月4日 · Nuclear microinjection of polyethyleneimine (PEI)–DNA polyplexes results in high transgene expression levels, showing unpacking can take ... tw | twEvaluating the Intracellular Stability and Unpacking of DNA ... - NCBIWe demonstrate a highly sensitive method to characterize the structural composition and intracellular fate of polymeric DNA nanocomplexes, ... tw | twDeep learning connects DNA traces to transcription to reveal ...2021年6月8日 · Furthermore, we explore methods to “unpack the black box” to determine in an unbiased manner which structural features of chromatin ...Chromatin Remodeling Complexes: The Regulators of GenomeHowever this packing and unpacking of chromatin need to temporally and spatially regulated for differential regulation of genomic functions like DNA ... tw | twStimulus-Responsive Peptide for Effective Delivery and Release of ...2018年3月2日 · Despite the importance of vector unpacking to free bound DNA cargo inside ... ODS-3 column (GL Sciences, Tokyo, Japan) at 25 °C (Figure S1). tw | twAdsorption of DNA Nitrogenous Bases on Nanodiamond Particles2018年4月20日 · Efficiency of adsorption of nucleic acid nitrogenous bases (NBs) on carboxylated detonation nanodiamond (DND–COOH) particles in aqueous ... tw | twGold Nanocluster Decorated Polypeptide/DNA Complexes for NIR ...During the delivery process, the efficient gene compaction, cross-membrane delivery and unpacking of cargoes in cytoplasm/nuclei for gene expression are ...Resolving DNA Damage: Epigenetic Regulation of DNA Repair - MDPIWhile the exact molecular mechanism that links damaged DNA sensing and chromatin unpacking at sites of heterochromatic DSBs is unknown, it might involve the ... tw | twA Photoactivatable AIE Polymer for Light‐Controlled Gene Delivery2015年6月19日 · ... vectors and the subsequent unpacking of nucleic acids in cytosol ... Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking twAdenovirus major core protein condenses DNA in clusters and ...2019年8月9日 · This condensation modulates the virion internal pressure and DNA ... in a similar unpacking experiment resulted in light emission in the ... |
延伸文章資訊
- 1复制叉式复制_百度百科
复制叉是不对称的,即一条子链是连续合成的,这是前导链,其合成稍稍领先于另一条不连续合成的后随链。由于DNA子链的合成是从5,端到3'端方向进行的,所以前导链只需在复制 ...
- 2複製叉 - 中文百科全書
複製叉(replication fork),有時也稱作生長點(growing point),是DNA複製時在DNA鏈上通過解旋、解鏈和SSB蛋白的結合等過程形成的Y字型結構。
- 3DNA複製- 維基百科,自由的百科全書
複製叉
- 4《Science》:人類首次可控DNA複製速度以殺死癌細胞!
在這項最新的研究中,科學家進行了大量實驗,解開了DNA複製時的複製叉動力機制與核苷酸原料合成之間的具體機制。 BOX:什麼是複製叉: 複製叉(replication ...
- 5The DNA Replication
DNA複製時形成複製叉(Replication fork),代表當雙股DNA打開時,DNA polymerase要能同時做5'→3' 與3'→5'兩個方向,但是DNA複製時. 只能由5'→3'的...